Friday, May 15, 2009

Update - We have a plan!!!

I FINALLY had my follow-up appointment with the RE yesterday after my FET c/p in March and my RPL panel bloodwork. I am so impressed with my RE. There is a reason that he's one of the best! He had spent a long time reviewing our chart and previous history and had a plan ready for us.

He first went over our RPL results. Everything came back normal EXCEPT that I have heterozygous Factor V Leiden. It's a blood clotting issue that means my blood is more prone to forming clots. He says that he does NOT think it has anything to do with our three loses, though. Apparently it's a big debate in the IF world because 10% of the population have Factor V, but only .5-1% of people have repeat pregnancy loss, so it may or may not be related. He said that our treatment options are taking aspirin or H.eparin injections. He discourages H.eparin, though, because the risks outweigh the gains.

His main conclusion is that our problems are a result of poor egg quality. With an FSH of 11.4, I'm above normal, which could indicate egg quality issues. His goal with our next IVF will be to try and improve egg quality by using "softer" stimulation and by adding growth hormone, which recent studies have shown to improve quality. He is also swiching L.upron to GnRH antagonist which won't give me such extreme headaches. We're hoping to get fewer eggs of better quality. In the past, they've retrieved 23 eggs each time but only about 14 have been mature and 9 fertilized (both cycles were pretty similar), although in the first cycle, my embryos after day 3 had poor quality and poor morphology. So, if we can have fewer eggs that are better quality and more able to fertilize, plus take aspirin for the Factor V, then maybe this is a recipe that will work!

Mr. C and have had our hope restored a bit after hearing what our RE had to say. We're ready to move along with this next cycle (probably in July). Mr. C. is feeling positive and supports this new plan, so that makes me feel so good!


Anonymous said...

I have been following your blog for a while now and am elated to read these two recent posts--YAY for this plan and the confidence inspired by your wonderful RE! I am so hopeful for you!!!

And, wow, I was so moved by the Willow tree angel exchange and your heartfelt tribute to the women you had met on BUMP. I actually found you via a comment on Kahla's blog (and was so intrigued by the name of your blog that I checked it out). I met K on an internet community. None of us enjoyed deferred parenthood and the heartache of infertility and loss BUT we surely did forge some amazing friendships!

Wishing all good things for you!


~Hollie said...

Just great to get a plan! Feeling renewed in your journey! thats great!!! We are all wishing you nothing but the best with your next cycle. I'm all for the less=more scenario. It worked for me!

Peeveme said...

It sounds like your RE is really tailoring your treatment for you and looking at recent research. I am really hoping this approach does the trick.

N said...

I am so glad you're back!!! I enjoy reading your posts whether its good news or bad, we're all in this TTC journey together!

Stuart and Sarah Creamer said...

I just found your blog and I am glad you have a new plan. It sounds a lot like our new plan for our 4th IVF- well actually 3rd full IVF. We have had 2 IVF's and a FET and all have resulted in negative pregnancies. Praying this time works for both of us!

Chelle said...

That's wonderful! I am excited that your RE has such a good grasp on things. Part of my protocol was to get better quality eggs, less quantity and it worked.... I SO hope it was for you. I am thinking of you.

Kahla said...

I'm so glad ya'll have a plan!!! I started baby aspirin this last time too! I hope this gives you your miracle and will be cheering you along!